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The reason for such differing sensitivities of CBCT and SWIFT MRI could be explained by the differences of contrast mechanisms of these two imaging modalities. The mobile water molecules usually filling the cracks do not significantly attenuate X-rays. Therefore, the signal amplitude in CBCT is linearly dependent on the portion of crack volume creating a negative contrast. Alternatively, in the case of MRI, the presence of water in a crack creates a positive contrast enhancement by two mechanisms: first, the concentration of water inside a crack is at least 5 times higher than that in the dentine; and second, the transverse relaxation rate (=1/T2) of mobile water in cracks is much smaller than that in motion-restricted dentine pores,14 which makes the signal from the water located in cracks less blurred and more localized inside of the same voxel.
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