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Drug-induced cell-line response prediction. We design and build NeRD to predict the cell-line response to a novel drug. NeRD uses the four extracted features to predict the cell-line response to the new drug. The details of each feature extractor and the designing process are introduced in the following sections.
We use the miRNA expression profile to represent the cell-line response feature. The miRNA expression profile of a cell line is obtained from the DrugMatrix database. The expression profile of each sample is represented using the binary vector. 827ec27edc